Initially called La Haye en Touraine, the town was the birthplace of the philosopher René Descartes (1596-1650), although his family home was in nearby Chatellerault.

Descartes left La Haye in approximately 1606 to attend the College Henri IV at La Flèche.

The town was renamed La Haye-Descartes in 1802 in his honour, and then renamed again to Descartes in 1967.

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