Târgu Mures is the seat of Mures County in the historical region of Transylvania, Romania. It is the 16th largest Romanian city, with 134,290 inhabitants as of the 2011 census. It lies on the Mures River, the second longest river in Romania (after the Danube).

The first fortress in the town was erected in 1492 upon order of voivode Stephen Báthory, and was accomplished somewhere between 1602 and 1652 under judge Tamás Borsos. Having a pentagon plan, surrounded by a defense wall, the Citadel has seven forts, five of them bearing the names of the guild which - according to tradition - supported its maintenance: the leather dressers', the tailors', the butchers', the ironmongers', the coopers'. After the Citadel was taken over by the Austrian troops, it became the headquarters of the military garrison based in the town. In the meantime the Baroque style building was built (on the left hand side of the road in front of the entrance gate) and in the second half of the 18th century the construction works of the "barkey" were started, an addition finished in the 19th century. On the occasion of the Târgu Mures days - which have as central point of performance the Citadel - a museum center was opened in the gate fort (erected in 1613) presenting the history of the town and of the Citadel.

The Teleki-Bolyai Library is a historic public library and current museum in the town. One of the richest Transylvanian collections of cultural artefacts, it was founded by the Hungarian Count Sámuel Teleki in 1802, at the time when Transylvania was part of the Habsburg Monarchy, and has been open to the reading public ever since. It was among the first institutions of its kind inside the Habsburg-ruled Kingdom of Hungary. It houses over 200,000 volumes, of which many are rarities, constituting a comprehensive scientific database. The book collection is divided into several smaller libraries, of which the two main donations are the original 40,000-volume Teleki Library and the 80,000-volume Bolyai Library; the rest, grouped as the Miscellaneous Collection, is made up of several private libraries, volumes previously held by religious schools and those of a Franciscan friary. Overall, the library constitutes a collection of most traditional types of Transylvanian book.

The old City Hall was built in 1906-1907 after the construction plans of Komor Marcell and Jakab Dezso. The entrance area, including the corridor and the staircase leading to the first floor, is the most representative in this regard. The ribbed stellar vaults that cover this area were inspired by Gothic architecture. The vaults are supported by columns with composite caps, and the keystone is a large floral shape which includes the lighting appliance. The vaults are painted with spiraling vegetal motifs. Elements of the front hall include the stone bench with its legs shaped as those of an animal and with wing-shaped handles. Its shell-shaped, golden back has a shield flanked by two volutes on its upper side. Features of the monumental staircase leading to the first floor include the upper side of the banister resembling a slithering animal or a wave. The exterior decoration is simpler and is based on Hungarian-Székely folk motives made of polychromatic ceramics. The ground floor is marked by a solid, embossed pedestal. Windows with large openings tend to be predominant in the façade. The three semicircular windows in the middle area of the façade are those of the honor hall that has a double elevation with respect to the other rooms. The glass paintings which illustrated Gábor Bethlen, Francis II Rákóczi, Lajos Kossuth, Ferenc Deák and Franz Joseph I of Austria are missing from the halls.

The Palace of Culture is a remarkable construction in the city center. It was built upon initiative of the mayor of the town, György Bernády. Building works started in the spring of 1911. They contributed to the establishment of the distinctively flavored Hungarian Art Nouveau school in Transylvania by their works in Deva and Oradea. The plan is an irregular rectangle, with protuberances on the sides and at the extremities. The building has five floors: a tall ground floor, a mezanine and three floors differentiated by the use of various construction materials. The façades are characterized by bi-dimensionality and by a liniar-rectangular style, with only a few curvilinear elements: the six bow-windows covered by semi-caps above the main portal and the circular balconies on the edges. The main entrance is in the middle of the façade on Enescu street and is made up of four massive doors, protected by an architectural element made of glass and with an iron framing. This element, as well as the doors decorated with iron floral motifs are typical for the early 20th century style. The exterior is richly decorated, with colored mosaic panels, with relieved scenes and busts of Hungarians. The mosaic on the main façade is an allegorical scene inspired by the Hungarian folklore. The cardboards were made by Nagy Sándor, a Hungarian artist, who founded with Körösföy Kriesch Aladár the School of Gödöllo. The art is characterized by bi-dimensionality and vertical rhythmicalness. Most of the mosaics and stained glass windows were authored by Róth Miksa, particularly those on the side facing Square.

The city skyline can be seen from Cornesti Heights.