Antequera lies 47 km north of the city of Málaga on the A45 highway, at the foot of the mountain ranges of El Torcal and Sierra de la Chimenea, 575 m above mean sea level. It occupies a commanding position overlooking the fertile valley bounded to the south by the Sierra de los Torcales, and to the north by the Guadalhorce River. At 817 km², the municipality is the largest, in terms of area, in the province of Málaga and one of the largest in Spain. The population is 41,197 (2002 census).

The saltwater lagoon Fuente de Piedra, which is one of the few nesting places of the Greater Flamingo in Europe, and the limestone rock formation of the Torcal, a nature reserve and popular spot for climbers, are nearby. Across the Guadalhorce is Peña de los Enamorados, ("The Lovers' Rock"), named after the legend of two young Moorish lovers from rival clans who threw themselves from the rock while being pursued by the girl's father and his men. This romantic legend was adapted by the English poet Robert Southeyfor his Laila and Manuel, in which the lovers were a Muslim girl and her father's Christian slave.