Pastrana is a medieval town and municipality in the province of Guadalajara, Castile-La Mancha, Spain, 40 kilometres (25 mi) southeast of the provincial capital, Guadalajara. It is notable as the site of the imprisonment of the one-eyed Princess of Éboli by Philip II of Spain after a court scandal in 1573, and also as the home since the 17th century of the Pastrana tapestries, a set of four Flemish tapestries depicting the attack of Alfonso V of Portugal on Morocco in 1471.

Important events are Semana Santa at Easter and La Fiesta in August, a week of events, such as concerts, parties, encierros and bullfights, with the town congregating in La Plaza every evening for a night of live music and dancing.