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Elephant and Castle is an area of South London, England, in the London Borough of Southwark. The name also informally refers to much of Walworth and Newington, due to the proximity of the London Underground station of the same name. The name is derived from a local coaching inn. The popular and enduring idea that the inn itself derives its name from an English corruption of the phrase La Infanta de Castilla, as a reference to Eleanor of Castile, has been debunked by local historian Stephen Humphrey in his 2013 book Elephant and Castle, a History.

The major traffic junctions here are connected by a short road called Elephant and Castle, the nascent part of the A3. Traffic runs to and from Kent along the A2 (New Kent Road and Old Kent Road), much of the south of England on the A3, to the West End via St George's Road, and to the City of London via London Road and Newington Causeway at the northern junction. Newington Butts and Walworth Road adjoin the southern junction. It forms part of the London Inner Ring Road and the boundary of the London congestion charge zone.

The subterranean River Neckinger, which originates in Geraldine Mary Harmsworth Park, flows east under the area towards St Saviour's Dock where it enters the Thames. The area was significantly remodelled in the 1960s as part of post-war reconstruction. A new wave of redevelopment began in the late 2000s with the demolition of the brutalist Heygate Estate. The various phases of the project are due to last until the late 2020s. The demolition of the shopping centre and The Coronet took place in 2021.

The Elephant has two linked London Underground stations, on the Northern and Bakerloo lines, and a National Rail station served by limited Southeastern services and Thameslink suburban loop line services to Mitcham, Sutton and Wimbledon, and services to Kentish Town and St. Albans to Orpington or Sevenoaks via Catford.