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Chiswick (pronounced "chizzick") is a district of west London, England. Most of it is in the London Borough of Hounslow. Other parts of the W4 postcode area, including Chiswick Park tube station, Acton Green, and much of Bedford Park are in the London Borough of Ealing. It contains Hogarth's House, the former residence of the 18th-century English artist William Hogarth; Chiswick House, a neo-Palladian villa regarded as one of the finest in England; and Fuller's Brewery, London's largest and oldest brewery. It occupies a meander of the River Thames used for competitive and recreational rowing, with several rowing clubs on the river bank. The finishing post for the Boat Race is just downstream of Chiswick Bridge.

Chiswick was historically the ancient parish of St Nicholas in the county of Middlesex, with an agrarian and fishing economy beside the river centred on Church Street. Having good communications with London from an early time, Chiswick became a popular country retreat, and as part of the suburban growth of London in the late 19th and early 20th centuries the population significantly expanded. It became the Municipal Borough of Brentford and Chiswick in 1932 and has formed part of Greater London since 1965, when it was merged into the London Borough of Hounslow. Sublocalities include Bedford Park, Grove Park, the Glebe Estate, Strand-on-the-Green and those with named tube stations, Turnham Green and Gunnersbury, within its three full-sized wards of the United Kingdom.

On a border, the Chiswick or Great West Road Roundabout is the start of the North Circular Road (A406), South Circular Road (A205) with the eponymous road flying over this. West of Chiswick's Hogarth Roundabout, the Great West Road from central London converts to the M4 motorway, providing a second mode of transport connection to Heathrow Airport and the M4 corridor. The Great Chertsey Road (A316) runs south-west from the Hogarth Roundabout, becoming the M3 motorway.

Historic figures who lived in Chiswick include the poets Alexander Pope and W. B. Yeats, the Italian revolutionary Ugo Foscolo, the Impressionist painter Camille Pissarro and the novelist E. M. Forster.

Chiswick was first recorded c.1000 as the Old English Ceswican meaning "Cheese Farm"; the riverside area of Duke's Meadows is thought to have supported an annual cheese fair up until the 18th century.