Cluses is a commune in the Haute-Savoie department in the Rhône-Alpes region in south-eastern France.

Citizens are known as Clusiens. The commune is situated in the Arve Valley, on the river which bears the same name. Cluses is known for its Alpine setting and (during the first part of the 20th century) its watch-making industry.

The town is located in the Arve Valley, in the region Faucigny. Situated between Geneva and Chamonix, Cluses is located near a number of popular ski slopes.

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