Guebwiller is a commune in the Haut-Rhin department in Alsace in north-eastern France.

It is situated 20 km (12 mi) northwest of Mulhouse at the foot of the Vosges mountains. The Ballon de Guebwiller, the highest point in the Vosges, lies 8 km (5.0 mi) to the west of the town.

In 2006, Guebwiller had a total population of 11,609 and its metropolitan area a population of 31,868.