Villasana de Mena is located in Castilla y León, Burgos, Villasana de Mena.

The Mena Valley is a municipality of the province of Burgos, bordering the provinces of Alava, Biscay and Cantabria.

The Mena valley has 3,926 inhabitants distributed among 43 small villages. Its capital, Villasana de Mena, has 1.554 inhabitants.