Wuppertal is a city in North Rhine-Westphalia, Germany, in and around the Wupper valley, east of Düsseldorf and south of the Ruhr. With a population of approximately 350,000, it is the largest city in the Bergisches Land. Wuppertal is known for its steep slopes, its woods and parks, and its suspension railway, the Wuppertal Schwebebahn. It is the greenest city in Germany, with two-thirds green space of the total municipal area. From any part of the city, it is only a ten-minute walk to one of the public parks or woodland paths.

In the 18th and 19th centuries, the Wupper valley was one of the largest industrial regions of continental Europe. The increasing demand for coal from the textile mills and blacksmith shops encouraged the expansion of the nearby Ruhrgebiet. Wuppertal still is a major industrial centre, being home to industries such as textiles, metallurgy, chemicals, pharmaceuticals, electronics, automobiles, rubber, vehicles and printing equipment.

Aspirin originates from Wuppertal, patented in 1897 by Bayer, as does the Vorwerk-Kobold vacuum cleaner.

The Wuppertal Institute for Climate, Environment and Energy and the European Institute for International Economic Relations are located in the city.

In total, Wuppertal possesses over 4,500 buildings classified as national monuments, most exemplifying styles such as Neoclassicism, Eclecticism, Historicism, Art Nouveau/Jugendstil and Bauhaus. The American TV station CNN recommends Wuppertal as one of 20 places worldwide to visit in the year 2020 because of the Schwebebahn, the architectural diversity and the Nordbahntrasse, a 22-kilometre (14 mi) cycle route across the city 2020.

Main sights include:

• Schwebebahn or floating tram. One of the city's greatest attractions is the globally unique suspended monorail Wuppertaler Schwebebahn, which was established in 1901. The tracks are 8 m (26 ft) above the streets and 12 m (40 ft) above the Wupper.
• Wuppertaler Schwebebahn Kaiserwagen A guided tour of the suspension railway in a special tram.
• Wuppertal Opera (Opernhaus Wuppertal).
• Concerthall Stadthalle , a fine piece of turn-of-the-century architecture with outstanding acoustics. Home of the Wuppertal Symphony Orchestra (Sinfonieorchester Wuppertal) (Stadthalle).
• Wuppertal Dance Theatre (Tanztheater Wuppertal), a world-famous centre of modern dance founded by the choreographer Pina Bausch.
• Engels-Haus, 18th century-architecturally typical of the region, it houses a permanent display of materials associated with the co-founder of modern Communism, Friedrich Engels.
• Wuppertal Zoo, a large, nicely landscaped zoo.
• Botanischer Garten Wuppertal, a municipal botanical garden.
• Arboretum Burgholz, an extensive arboretum.
• Von der Heydt Museum is an important art gallery with works from the 17th century to the present time. The first of Picasso's works that ever appeared in public was displayed here.
• Skulpturenpark Waldfrieden, a sculpture park with exhibition hall, founded by sculptor Tony Cragg.