Agüimes is a Spanish town and municipality in the eastern part of the island of Gran Canaria in the Las Palmas province in the Canary Islands.

Agüimes is situated 5 km from the coast, and 26 km south of the island capital Las Palmas. The GC-1 motorway passes east of the town.

The population is 30,214 (2013), and the area is 79.28 km². The elevation is 275 m.

The district was not at one time a major tourist destination, but after the careful restoration of the old town, this has become the best example of a traditional Canarian hill town. The streets of the old town exude a gentle, relaxed, timeless atmosphere, and the carefully positioned street statues and sculptures add a series of surprises to a visit to the old town. The local plan for 'rural tourism' has led to the development of other small visitor centres on the district, the biggest of which is in the Guayadeque ravine. This area has many cave houses dating back hundreds of years, and a complete village excavated into the hillside, still occupied today, with its own cave chapel, cave bar and cave restaurants.

The Temisas Astronomical Observatory, on Montaña de Arriba near Temisas, is a popular visitor attraction, offering regular events related to astronomy.

In the centre of the town, the large, domed Church of San Sebastián in Plaza Nuestra Señora del Rosario is a noted example of Canarian Neoclassical architecture. Construction of the church started in 1796 and it was only completed in 1940.

Twenty-three kilometres (14 miles) south-west of Agüimes on the south coast of the island there stands a full-scale replica of the San Sebastián Church. It was erected in 2014 by the hotelier Eustasio López González, who originated from Agüimes, as part of a luxury hotel complex, the Lopesan Costa Meloneras Hotel in Maspalomas. The hotel consists of buildings designed in a Canarian Spanish Colonial Revival style to recreate the historic environment of Agüimes, including a copy of the church.

The Agüimes municipality's territory is rich in historical sites, among which the El Maipés necropolis in Agaete is a well-known site. The caves and granaries of the Audience site in Temisas and the caves and hillocks in Avila have been declared Sites of cultural interest in 2016.