Almendralejo is a town in the Province of Badajoz, Extremadura, Spain. It is situated 45 km south-east of Badajoz, on the main road and rail route between Mérida and Seville. As of 2010, it has a population of 33,975. It was the site of a battle and massacre in 1936 during the Spanish Civil War.

Almendralejo is situated about 45 km (28 mi) to the southeast of Badajoz on the railway line between Seville and Mérida. It is to the south of the River Guadiana on an extensive plain, with the slightly raised area to the south being known as the Tierra de Barros. The town grew rapidly at the end of the nineteenth century as the roads and railways were developed. It has broad streets and handsome buildings. The economy is centred on agriculture with extensive cultivation of cereals, fruit and grapes. There are many vineyards around the town, with a local red wine being produced, and the area is also known for the production of brandy.

Notable historical buildings of Almendralejo include the church of the Purification, the Iglesia Parroquial de Nuestra Señora de la Purificación, finished in 1515, in Gothic style. It has a well-proportioned tower and a seventeenth century retablo (devotional painting). The Palacio del Marqués de Monsalud is a seventeenth century building now used as council offices. The building surrounds a central courtyard, and on the ground floor there are arches mounted on pink granite columns, and a pedestal decorated with eighteenth century Seville tiles; on the first floor there is a red ceramic balustrade supported by small granite columns with arches. It was the birthplace of the revolutionary poet José de Espronceda, and houses a museum of Roman antiquities found in the region.

Carolina Coronado (full name: Victoria Carolina Coronado y Romero de Tejada} (12 December 1820 - 15 January 1911) was a Spanish writer, famous for her poetry, considered the equivalent of contemporary Romantic authors like Rosalía de Castro. As one of the most well-known poets writing in mid-19th-century Spain, she also played a diplomatic role (she was married to Horatio Perry, the American Secretary of the U.S. Legation in Madrid.) She both negotiated with the Spanish royal family in private and, through a series of widely published poems, promoted the aims of the Lincoln administration, especially abolition of slavery.