Trujillo is a municipality located in Extremadura, an autonomous community of Spain in the Province of Cáceres. It had 9,086 inhabitants (INE Census, 2013). Originally settled on a granite knoll which was readily fortified, the town now extends to the south-east of its original site. Trujillo is both a centre for tourism, with over 25 hotels, and a regional market town.

The old town contains many medieval and renaissance buildings. Many of these were built or enriched by the conquistadors born in the city. These include, the conquerors of Peru, Francisco Pizarro and his brothers, Francisco de Orellana and Hernando de Alarcón. Pizarro's equestrian statue stands in the main square, the Plaza Mayor. The most important monuments are the castle (old Berber fortress), the church of Santa María (thirteenth century), and the church of San Francisco.

It hosts the national cheese festival in early May.

Trujillo has a rich heritage. Among the most important monuments are the Castle (Alcazaba), the church of Santiago, the church of Santa María la Mayor, the church of San Francisco, the Church of San Martín, the Plaza Mayor, and renaissance palaces such as the palace of the Marquis of the Conquest, the palace of the Orellana-Pizarro family, the palace of the Duques de San Carlos, Marquesado de Piedras Albas, the house of the strong Altamirano, Palace Chaves (Luis Chaves Old), and of course the walled old town.

The Palacio de Piedras Albas was built circa 1530 by Don Pedro Suárez de Toledo, formerly owned by the Orellana Toledo family, the Marqueses de Orellana and later by the Marqueses de San Juan de Piedras Albas.

It has several museums: Museum of Coria (Javier Salas Foundation), Pizzaro's House, Enrique Elías Museum (local designer), Museum of Cheese and Wine.