Cannobio is a town and comune on the river Cannobino and the shore of Lago Maggiore in Piedmont, Italy.

The large lakefront piazza named after King Victor Emmanuel III was given a major refurbishment when in the winter of 2003-04 it was completely relaid in cobblestones and granite slabs. Also added was of a set of wide flagstone steps down to the lake, where people may sit and watch the lake steamers come and go from the landing stages nearby, and the sailing boats and wind-surfers skimming across the lake.

Some of the buildings both on the lakefront and further back in the old part of town date back over 600 years, from when Cannobio was a renowned smuggling town, and most of these have been restored in fine style.

From one, Giuseppe Garibaldi addressed the people of Cannobio in 1859, and on another stands a plaque celebrating an important event in Cannobio in 1627. Each building is painted a different colour, creating a traditional Italian port scene. To one side of the Piazza is Cannobio's old harbour, which houses the sailing, rowing and speedboats belonging to the locals.

The Santuario della Pietà church commemorates the events of 1522, when a painting of the Virgin Mary was believed to have bled. With its open dome it stands by the lakeside. The painting itself is now housed in another church in the town, and though it is not removed itself, a "Sacra Costa", representing the painting, is processed through the streets on 7 January every year.

Cannobio has its own "Lido" at the north end of town with a large sandy beach. The beach has a European Union Blue Flag for its cleanliness and facilities.