Puerto de la Cruz is a city and municipality in the northern part of the island of Tenerife, Canary Islands, Spain. It was formerly known by its English translation, "Port of the Cross", although now it is known in all languages by its Spanish name. It is located on the north coast, 4 km (2 mi) northwest of La Orotava, and 30 km (19 mi) west of Santa Cruz de Tenerife. The TF-5 motorway passes through the municipality. In Spanish the inhabitants are known as Portuenses. With an area of 8.73 km2 (3 sq mi), the municipality is the smallest in Tenerife.

The population is 30,483 (2018). The elevation of the town centre is 9 m (30 ft) AMSL. The highest point is Las Arenas, a volcanic cone with an elevation of 249 m (817 ft).

Tourism is an important industry in Puerto de la Cruz, as evidenced by the number of large hotels visible on the skyline.

Puerto de la Cruz is frequented by Northern Europeans during the winter months, due to its mild climate, and is particularly popular over Christmas and the New Year periods.

The Western European tourist contingent to Puerto de la Cruz tends to consist more of mature couples, in contrast to resorts such as Playa de las Americas.

The summer months see more Spanish tourists, particularly during August, when conditions on the Spanish mainland can be excessively hot.