San Cristóbal de La Laguna (commonly known as La Laguna is a city and municipality in the northern part of the island of Tenerife in the Province of Santa Cruz de Tenerife, on the Canary Islands. The city is the third-most populous city of the archipelago and the second-most populous city of the island. La Laguna's historical center was declared a World Heritage Site by UNESCO in 1999. In 2003 the municipality started an ambitious Urban Plan to renew this area, that was carried out by the firm AUC S.L. (Arquitectura Urbanismo y Cooperación). The city was the ancient capital of the Canary Islands. La Laguna lies right alongside the city of Santa Cruz de Tenerife; thus, the two cities and municipalities form a single large urban center, linked by tram.

The city is home to the University of La Laguna which is home to 30,000 students; these are not included in the population figures for the city. La Laguna is considered to be the cultural capital of the Canary Islands. Also there is in the habit of being calling the "Ciudad de los Adelantados", for having been the first university city of the archipelago.

Its economy is business-oriented while agriculture dominates the northeastern portion of the city. The urban area dominates the central and the southern parts. Tourism covers the northern coast. The main industry includes some manufacturing. The industrial area is made up of the main subdivisions of Majuelos, Las Torres de Taco, Las Mantecas and Las Chumberas. In this city one finds the legendary house of the spectre of Catalina Lercaro, as well as the incorrupt body of Sor María de Jesús, and the Christ of La Laguna (Cristo de La Laguna). Another emblematic building of the city is the Cathedral of La Laguna, which is the Catholic cathedral of Tenerife and its diocese (Diocese of Tenerife).

Other important historical figures of the city were Amaro Pargo, one of the famous corsairs of the Golden Age of Piracy, and José de Anchieta, Catholic saint and missionary and founder of the cities of São Paulo and Rio de Janeiro in Brazil.

In 2010, after a survey, La Laguna was listed as the city with the best reputation in the Canary Islands and the third provincial capital city of Spain with the best reputation, behind Gijon and Marbella.