Alhama de Murcia is a Spanish municipality in the autonomous community of the Region of Murcia. It is located in the north of the southern half of the region. The municipality shares borders with Librilla in its north, Murcia in its northeast, Fuente Álamo de Murcia in its east, Mazarrón in its south, Totana in its west and Mula in its northwest.

The west of Sierra de Carrascoy mountain range occupies part of the east of Alhama de Murcia. Guadalentín River traverses the municipality from its south-west to its north-east. The territory is especially raised in the north-west, where some raised landforms occur and the south-eastern foot of Sierra Espuña mountain range occurs, and even the norht-west end of Alhama de Murcia occupies the mountain range itself.