Nenagh, the largest town in northern County Tipperary, lies to the west of the Nenagh River, which empties into Lough Derg at Dromineer, 9 km to the north-west, a centre for sailing and other watersports. The Silvermine Mountain range lies to the south of the town, with the highest peak being Keeper Hill (Irish: Sliabh Coimealta) at 694 m. The Silvermines have been intermittently mined for silver and base metals for over seven hundred years. Traces of 19th century mine workings remain.

Sightes include:

• The town's historic features include Nenagh Castle, the Heritage Centre and the ruined Franciscan abbey. This fine Norman Keep was built c. 1200 by Theobald Walter, 1st Baron Butler and completed by his son Theobald le Botiller c1220. The circular keep is over thirty metres high and its base has a diameter of sixteen metres. It is one of the finest of its kind in Ireland. The crown of crenellations and ring of clerestory windows were added at the instigation of Bishop Michael Flannery in 1861. The intention was that the keep would become the Bell tower of a Pugin-designed cathedral that was never built. Though not true to historic character, these additions have ensured the iconic status of the keep which ensures that it features on the logos of many local clubs and businesses including Nenagh Town Council. The Castle and grounds were extensive renovated between 2009 and 2013. This project is aimed to position the castle as the main tourist attraction in the area. It is now open to the public.
• The old jail, with its octagonal governor's residence, is now an historic monument. Only one jail block remains intact. The Governor's Residence and jail gatehouse house Nenagh & District Heritage Centre.
• Nenagh Courthouse was built in 1843 to the design of architect John B. Keane. The design was similar to his previous courthouse in Tullamore, which in turn followed William Morrison's designs for Carlow and Tralee. In 2002 the grounds of the refurbished courthouse became the site of bronze sculptures of Matt McGrath, Bob Tisdall and Johnny Hayes, three Olympic gold medalists with Nenagh links. After the county council moved to their new Civic Offices in 2005, the courthouse was subsequently refurbished.
• Nenagh Arts Centre (formerly the Town Hall) is a distinctive building built in 1895. It was refurbished and now features a theatre and multi-purpose exhibition space. Until 2005 it housed the offices of Nenagh Town Council and up until the 1980s Nenagh Public library. The building was designed by the then Town Engineer Robert Gill (father of Tomas Mac Giolla)
• St Mary's of the Rosary Catholic Church is a neo-gothic church and was built in 1895 to a design by architect Walter G Doolin. It was constructed by John Sisk using Lahorna stone and Portroe slate with the Portland stone of the arches being the only imported material.
• The adjacent St Marys Church of Ireland Church was built in 1862 to a design by the architect Joseph Welland (1798-1860) and features a stained glass window from the studio of Harry Clarke. The building is striking in its simplicity in contrast to its larger and more ornate neighbour.
• The town also contains the ruins of a Franciscan Friary, where the Annals of Nenagh were written and the medieval Priory of St John on the outskirts of the town at Tyone.
• The new Civic Offices on the Limerick Road house Tipperary County Council offices. Designed by ABK Architects, they have won international recognition for their striking modern design.
• Nenagh Hospital, known locally as St. Joseph's Hospital, located on the Thurles Road (c1940). It is the only general hospital in north Tipperary. Built in the International Style of mostly flat roof and rendered walls the hospital was retro-fitted with uPVC windows at a later date. There is an adjoining mortuary church with notable mosaics and stained glass.
• The mixed residential scheme known as 'Stafford Hall' Silver Street Nenagh was selected for exhibition in the R.I.A.I Architectural Awards in 2004.